Blar i forfatter "Indrevik, Jill-Tove"

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    • Expression and function of Leukotriene B4 receptors in human articular chondrocytes 

      Hansen, Ann Kristin; Indrevik, Jill-Tove; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur (Conference object; Konferansebidrag, 2013)
      Leukotriene B4 (LTB4) is linked to osteoarthritis (OA) development however the expression of LTB4 receptors in cartilage cells and the physiological effects of LTB4 on cartilage tissue remain unknown. In this study we find that human articular chondrocytes express LTB4 receptors and that these receptors are functional, however, LTB4 does not seem to affect importantly some primary chondrocyte functions.

    • Human articular chondrocytes express functional Leukotriene B4 receptors 

      Hansen, Ann Kristin; Indrevik, Jill-Tove; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-09)
      Leukotriene B<sub>4</sub> (LTB<sub>4</sub>) is a potent chemoattractant associated with the development of osteoarthritis (OA), while its receptors BLT1 and BLT2 have been found in synovium and subchondral bone. In this study, we have investigated whether these receptors are also expressed by human cartilage cells and their potential effects on cartilage cells. The expression of LTB<sub>4</sub> ...